SEMAX (MEHFPGP) is a synthetic heptapeptide derived from an ACTH (4–10) fragment, commonly described as an ACTH(4–7) motif stabilized with a C-terminal Pro-Gly-Pro sequence, and studied in experimental models for melanocortin-pathway signaling and neurotrophin gene-expression regulation (e.g., BDNF/TrkB)
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